- It should provide a controlled environment of optimum biomass yields.
- It should permit aseptic fermentation for a number of days reliably and dependably, and meet the requirements of containment regulations Containment involves prevention of escape of viable cells from a fermenter or a downstream processing equipment into the environment.
- It should provide adequate mixing and aeration for optimum growth and production, Without damaging the microorganisms.
- The power consumption should be minimum,
- It should provide easy and dependable temperature control.
- Facility for sampling should be provided.
- It should have a system for monitoring and regulating pH of the fermentation broth.
- Evaporation losses should be as low as possible.
- It should require a minimum of labour in maintenance, cleaning, Operating and harvesting operations.
- It should be suitable for a range of fermentation processes. But this range may often be restricted by containment regulations.
- It should have smooth production internal surfaces, and joints should be welded wherever possible.
- The pilot scale and production stage fermenters should have similar geometry to facilitate scale-up.
- It should be contrasted using the cheapest materials that afford satisfactory results.
- There should be adequate service provisions for individual plants.
Biotechnology is "the integrated use of of biochemistry, microbiology And engineering science in order to achieve technological application of the capabilities of micro-organisms, cultured tissue/cells and parts thereof." Biotechnology consists of "the controlled use of biological agents, Such as, micro-organisms or cellular components, for beneficial use."
Tuesday, 20 April 2021
Basic Functions of a Fermenter
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